HIV co-infection influences natural selection on M. tuberculosis

While M. tuberculosis has been evolving with humans for thousands of years, HIV co-infections create host immunological environments that this bacterium has not encountered before and could, therefore, be nudging it to evolve new characteristics. Now, an evolutionary analysis of M. tuberculosis full genome sequences from HIV uninfected and HIV co-infected individuals uncovered specific sites within M. tuberculosis genomes where the bacterium may have been compelled to evolve in response to HIV-1 co-infections.

Journal of Parkinson’s Disease celebrates key breakthroughs

Amsterdam, The Netherlands, March 21, 2017 - Marking the 200th anniversary of James Parkinson's first published description of the disease that would come to bear his name, the Journal of Parkinson's Disease is proud to publish Milestones in 200 Years of Parkinson's Disease Research. This special issue features commentaries by luminaries in the field, who are responsible for some of the greatest advances in understanding and treating the disease since it was first characterized.

‘Geofencing’ shows promise in tracking chronic care

Location-tracking apps on smartphones could be used to help track and manage care for thousands of patients who suffer from chronic diseases, and possibly even provide feedback to them on lifestyle changes that could help, according to an initial assessment by researchers at UC San Francisco.

Individuals with autism at substantially heightened risk for injury death

Deaths in individuals with autism increased 700 percent in the past 16 years and were three times as likely as in the general population to be caused by injuries, according to a new study by Columbia University's Mailman School of Public Health. The average age at death for individuals with autism was 36 years younger than for the general population, 36 years of age compared with 72.